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In honor of the ATS centennial anniversary, we were pleased to provide a historical overview of asthma pathogenesis The complex phenotype of allergic bronchial asthma involves a variable degree of bronchoobstruction, The classic signs and symptoms of asthma are intermittent dyspnea, cough, and wheezing. Pathology of asthma Anatomical change Multicellular inflammation Which are factors contributed to asthma Disruption of Airway Epithelium in Asthma Pathogenesis: Are Protozoa Responsible? Rafael Martnez-Girn, M.D., Ph.D Review article. A new look at the pathogenesis of asthma. Stephen T. Holgate*, Hasan S. Arshad*, Graham C. Roberts*, In this issue, Huang et al. (J Allergy Clin Immunol 2011;127: 372-381.e3), reporting on behalf of the
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